Coumarins and derivatives
Medchemexpress LLC 7-Methylcoumarin | 2445-83-2 | 1 ML
7-Methylcoumarin is a coumarin derivative known for its potent hepatoprotective and antioxidant properties. It acts as a mechanism-based inhibitor for CYP2A6 and has been shown to reduce liver damage markers and oxidative stress. It significantly reduces alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum bilirubin (TB) in rats with CCl4-induced liver damage, while restoring total protein (TP) and albumin (TA) levels in serum.
- Acts as a mechanism-based inhibitor for human CYP2A6.
- Causes chromosomal aberrations in A. sativum Promeristem.
- Restores elevated levels of ALT and AST to near normal in rats.
- Restores antioxidant enzyme and TBARS levels.
- Restores serum TB and TP levels to near normal.
- Reduces hepatic lesions induced by CCl4.
Medchemexpress LLC HY-111919 10mg Medchemexpress, 3-Nitrocoumarin CAS:28448-04-6 Purity:>98%
Medchemexpress, HY-111919 10mg 3-Nitrocoumarin CAS:28448-04-6 3-Nitrocoumarin (3-NC) is a potent and selective Phospholipase C-γ (PLC-γ) inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC 3-Nitrocoumarin 28448-04-6 5mg
3-Nitrocoumarin (CAS 28448-04-6) is a selective inhibitor of phospholipase C- (PLC- ) an enzyme involved in cellular signal transduction through the hydrolysis of membrane phospholipids and subsequent generation of secondary messengers By suppressing PLC- catalytic activity 3-Nitrocoumarin disrupts related intracellular signaling pathways thereby enabling investigation of PLC- -mediated mechanisms in various physiological and pathological contexts This compound is widely utilized in studies focused on elucidating the roles of PLC- in disease models and fundamental biomedical research
eMolecules 6-Fluoro-4-hydroxycoumarin | 1G | Ships from Wood Dale, IL | Chem-Impex | 1994-13-4 | MFCD03094006 | MW: 180.13
Chem-Impex | 6-Fluoro-4-hydroxycoumarin | 1G | 1994-13-4 | MFCD07383035 | MW:177.22
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Selleck Chemical LLC Dicoumarol S4299-200mg
Dicoumarol is a competitive NADPH quinone oxidoreductase (NQO1) inhibitor and used as an anticoagulant by interfering with the metabolism of vitamin K
Cayman Chemical 4-HydroxycoumarIn 250g
A coumarin; inhibits vitamin K1 epoxidation and prothrombin synthesis by 18 and 67%, respectively, in cell-free assays at 6.2 mM; has been used in the synthesis of anticoagulants, as well as antithrombotic, anti-inflammatory, antibacterial, and antifungal agents
Medchemexpress LLC 7-Methylcoumarin | 2445-83-2 | MFCD00006880 | 25 G
7-Methylcoumarin is a coumarin derivative with potent hepatoprotective and antioxidant properties. It acts as a mechanism-based inhibitor for CYP2A6, significantly decreasing ALT, AST, and serum bilirubin in rats with CCl4-induced liver damage. It also restores total protein and albumin levels in serum while preventing oxidative stress, and can decline mitotic activity of *A. sativum* promeristem.
- Coumarin derivative
- Potent hepatoprotective and antioxidant properties
- Mechanism-based inhibitor for CYP2A6
- Decreases ALT, AST, and serum bilirubin in rats with CCl4-induced liver damage
- Restores total protein and albumin levels in serum
- Prevents oxidative stress
- Can decline mitotic activity of *A. sativum* promeristem
- Purity: 99.34%
- Appearance: Solid, white to off-white
Pfaltz & Bauer 7-Hydroxy-4-methylcoumarin 98% 100G | 90-33-5
7-Hydroxy-4-methylcoumarin 98% 100G | 90-33-5
